3-(tert-Butyldimethylsilyl)morphinone

• Catalog No.: B691325
• CAS Number: 91265-75-7
• M. F.: C23H31NO3Si
• M. W.: 397.58264

SYNONYMS

• IUPAC name: (1S,5S,13R,17R)-10-[(tert-butyldimethylsilyl)oxy]-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10,15-tetraen-14-one
• IUPAC Traditional name: (1S,5S,13R,17R)-10-[(tert-butyldimethylsilyl)oxy]-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10,15-tetraen-14-one
• Synonyms: (5α)-7,8-Didehydro-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4,5-epoxy-17-methyl-morphinan-6-one

DATABASE IDS

• CAS Number: 91265-75-7

PROPERTIES

• Apperance: Yellow Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Methanol

DETAILS

Description (English)

Protected Morphinone (M652350), a toxic metabolite of Morphine.

REFERENCES

• James, R., et al.: J. Pharmacol. Exp. Ther., 221, 708 (1982)
• Yamano, S., et al.: J. Biol. Chem., 260, 5259(1982)
• Ishida, T., et al.: Drug Metab. Dispos., 17, 77 (1982)
• Yamano, S., et al.: Xenobiotica, 27, 645 (1982)