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4-tert-Butyldimethylsilyl-5'-chloro-4a'-hydroxy-6'-(hydroxyimino)methyl Simvastatin_Molecular_structure_CAS_123852-22-2)
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4-tert-Butyldimethylsilyl-5'-chloro-4a'-hydroxy-6'-(hydroxyimino)methyl Simvastatin

Catalog No. B691175 Name Toronto Research Chemicals
CAS Number 123852-22-2 Website http://www.trc-canada.com
M. F. C31H52ClNO7Si Telephone +1 (416) 665-9696
M. W. 614.28558 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer, Under inert atmosphere Chembase ID: 163327

SYNONYMS

IUPAC name
(1S,3S,4S,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-6-oxooxan-2-yl]ethyl}-4-chloro-4a-hydroxy-3-[(1E)-(hydroxyimino)methyl]-7-methyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate
IUPAC Traditional name
(1S,3S,4S,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-6-oxooxan-2-yl]ethyl}-4-chloro-4a-hydroxy-3-[(1E)-(hydroxyimino)methyl]-7-methyl-2,3,4,7,8,8a-hexahydro-1H-naphthalen-1-yl 2,2-dimethylbutanoate
Synonyms
[1S-[1α,3α,4β,4aα,7β,8β(2S*,4S*)]]-2,2-Dimethylbutanoic Acid 4-Chloro-8-[2-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3-[(hydroxyimino)methyl]-7-methyl-1-naphthalenyl Ester

DATABASE IDS

CAS Number 123852-22-2

PROPERTIES

Certificate of Analysis Download
Apperance Light Brown Solid
Solubility Chloroform
Solubility Dichloromethane
Solubility Ethyl Acetate
MSDS Link Download
Storage Condition -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)
Intermediate for the preparation of Simvastatin analogs as HMG-CoA reductase inhibitors.

REFERENCES