4-tert-Butyldimethylsilyl-5'-chloro-4a'-hydroxy Simvastatin

• Catalog No.: B691170
• CAS Number: 123852-10-8
• M. F.: C31H53ClO6Si
• M. W.: 585.28742
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S,3R,4S,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-6-oxooxan-2-yl]ethyl}-4-chloro-4a-hydroxy-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate
• IUPAC Traditional name: (1S,3R,4S,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-6-oxooxan-2-yl]ethyl}-4-chloro-4a-hydroxy-3,7-dimethyl-2,3,4,7,8,8a-hexahydro-1H-naphthalen-1-yl 2,2-dimethylbutanoate
• Synonyms: 2,2-Dimethylbutanoic Acid [1S-[1α,3α,4β,4aα,7β,8β(2S*,4S*)]]-4-Chloro-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester

DATABASE IDS

• CAS Number: 123852-10-8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 49-51°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Intermediate for the preparation of Simvastatin analogs as HMG-CoA reductase inhibitors.