O-tert-Butyl-dimethylsilyl Curcumin

• Catalog No.: B691020
• CAS Number: 911292-36-9
• M. F.: C27H34O6Si
• M. W.: 482.64076

SYNONYMS

• IUPAC name: (1E,6E)-1-{4-[(tert-butyldimethylsilyl)oxy]-3-methoxyphenyl}-7-(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
• IUPAC Traditional name: (1E,6E)-1-{4-[(tert-butyldimethylsilyl)oxy]-3-methoxyphenyl}-7-(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
• Synonyms: (1E,4Z,6E)-7-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one

DATABASE IDS

• CAS Number: 911292-36-9

PROPERTIES

• Apperance: Brown Gel
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol

DETAILS

Description (English)

Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhi

REFERENCES

• Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953)
• Tu, B., et al.: J .Cell Biol., 164, 341 (1953)
• Xu, G., et al.: Biochemistry, 44, 9817 (1953)
• Johnson, J., et al.: Cancer Lett., 255, 170 (1953)