Buserelin Acetate

• Catalog No.: B689740
• CAS Number: 68630-75-1
• M. F.: C62H90N16O15
• M. W.: 1299.4762
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(tert-butoxy)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl]-N-ethylpyrrolidine-2-carboxamide; acetic acid
• IUPAC Traditional name: (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(tert-butoxy)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(3H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl]-N-ethylpyrrolidine-2-carboxamide; acetic acid
• Synonyms: Suprafact; Suprecur; Supremon; 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor Monoacetate; Estomal

DATABASE IDS

• CAS Number: 68630-75-1

PROPERTIES

• Apperance: White Solid
• Melting Point: 186-188°C
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Gondadotropin-releasing hormone agonist, used to treat hormone-responsive cancers such as prostate and breast cancer. Synthetic nonapeptide agonist analog of LH-RH. Antineolpastic (hormonal).

REFERENCES

• Lam, P., et al.: Gynecol. Endocrinol., 24, 674 (2008)
• Chi, K., et al.: J. Urol., 180, 565 (2008)
• Menchaca, A., et al.: Theriogenol., 72, 477 (2008)
• Harada, T., et al.: Fertility and Sterility, 91, 675 (2008)