cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate

• Catalog No.: B685405
• CAS Number: 61397-56-6
• M. F.: C18H15BrCl2O4
• M. W.: 446.1193
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: [(2R,4R)-2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl benzoate
• IUPAC Traditional name: [(2R,4R)-2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl benzoate
• Synonyms: (2R,4R)-rel-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-methanol Benzoate; 2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-methanol

DATABASE IDS

• CAS Number: 61397-56-6

PROPERTIES

• Apperance: White Solid
• Melting Point: 118-120°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate is an intermediate in the preparation of antifungal agents such as Ketoconazole (K186000), Itraconazole (I937500) and Terconazole.

REFERENCES

• Heeres, J. et al.: J. Med. Chem., 26, 611 (1983)