6-Bromo-3,4-dihydro-2H-isoquinolin-1-one_Molecular_structure_CAS_147497-32-3)

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6-Bromo-3,4-dihydro-2H-isoquinolin-1-one
Catalog No.	B683520	Name	Toronto Research Chemicals
CAS Number	147497-32-3	Website	http://www.trc-canada.com
M. F.	C9H8BrNO	Telephone	+1 (416) 665-9696
M. W.	226.06992	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 68122

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SYNONYMS

IUPAC name

6-bromo-1,2,3,4-tetrahydroisoquinolin-1-one

IUPAC Traditional name

6-bromo-3,4-dihydro-2H-isoquinolin-1-one

Synonyms

6-Bromo-3,4-dihydroisoquinolin-1(2H)-one

6-Bromo-3,4-dihydro-1(2H)-isoquinolinone

DATABASE IDS

CAS Number

147497-32-3

PROPERTIES

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DETAILS

Description (English)

Intermediate used in the synthesis of benzolactams as dopamine D3 receptor ligands.IT is also used in the synthesis of new, selective 3-aminopyrazole based MK2-inhibitors that was proved to inhibit intracellular phosphorylation of hsp27 as well as LPS-ind

REFERENCES

Velcicky, J., et al.: Bioorg. Med. Chem. Lett., 20, 1293 (2011)
Ortega, R., et al.: Bioorg. Med. Chem. Lett., 21, 2670 (2011)