14-Bromo Daunorubicin Formate Salt

• Catalog No.: B682790
• M. F.: C28H30BrNO12
• M. W.: 652.4413
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-8-(2-bromoacetyl)-6,8,11-trihydroxy-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione; formic acid
• IUPAC Traditional name: (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-8-(2-bromoacetyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione; formic acid
• Synonyms: 14-Bromodaunomycin Formate Salt; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromoacetyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Formate

PROPERTIES

• Apperance: Red Solid
• Melting Point: 167-170°C (dec.)
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Adriamycin analogue; use as anticancer agent.

REFERENCES

• Krishan, A., et al.: Cancer Res., 41, 2745 (1981)
• Mueller, M., et al.: Eur. J. Biochem., 140, 447 (1981)