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Brassicasterol

Catalog No. B676850 Name Toronto Research Chemicals
CAS Number 474-67-9 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
(1S,2R,5S,10S,11S,14R,15R)-14-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-7-en-5-ol
IUPAC Traditional name
brassicasterol
Synonyms
Ergosta-5,22(E)-dien-3β-ol
(3β,22E)-ergosta-5,22-dien-3-ol
24-Methylcholesta-5,22-dien-3β-ol
Brassicasterin
24(R)-Methylcholesta-5,22E-dien-3β-ol
Δ5,22-Ergostadien-3β-ol
Δ5,22-Ergostadienol
ergosta-5,22-dien-3β-ol

DATABASE IDS

CAS Number 474-67-9

PROPERTIES

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DETAILS

Description (English)
A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway.

REFERENCES

  • Bishop, G.J., et al.: Plant Cell Physiol. 42, 114, (2001)
  • Fernandez, C., et al., Biochem. J. 366, 109 (2001)