Bodipy Cyclopamine-d10

• Catalog No.: B674802
• M. F.: C49H70BF2N5O4
• M. W.: 841.9190064

SYNONYMS

• IUPAC name: 4-(2-{[5-({2-[(3S,7'aR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3'H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-4'-yl]ethyl}carbamoyl)(^2H₁₀)pentyl]carbamoyl}ethyl)-2,2-difluoro-10,12-dimethyl-1λ^5,3-diaza-2-boratricyclo[7.3.0.0^3,^7]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide
• IUPAC Traditional name: 4-(2-{[5-({2-[(3S,7'aR)-3-hydroxy-3',6',10,11b-tetramethyl-2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a-hexadecahydro-1H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-4'-yl]ethyl}carbamoyl)(^2H₁₀)pentyl]carbamoyl}ethyl)-2,2-difluoro-10,12-dimethyl-1λ^5,3-diaza-2-boratricyclo[7.3.0.0^3,^7]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide

DETAILS

Description (English)

A labelled fluorescent Cyclopamine derivative that retains potency in Shh signaling inhibition (IC50=150nM).

REFERENCES

• Chen, K.J., et al.: Genes Develop., 16, 2743 (2002)