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(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine_Molecular_structure_CAS_380499-07-0)
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(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

Catalog No. B657140 Name Toronto Research Chemicals
CAS Number 380499-07-0 Website http://www.trc-canada.com
M. F. C20H16F7NO2 Telephone +1 (416) 665-9696
M. W. 435.3353624 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 162612

SYNONYMS

IUPAC name
(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-oxazine
IUPAC Traditional name
(2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-oxazine

DATABASE IDS

CAS Number 380499-07-0

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Solubility Chloroform
Solubility Ethyl Acetate
MSDS Link Download

DETAILS

Description (English)
Intermediate in the preparation of enantiomerically pure Aprepitant diastereomers and derivatives.

REFERENCES

  • Huskey, S., et al.: Drug Metab. Disposition, 32, 246 (2004)