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BLI 489 Hydrate_Molecular_structure_CAS_623564-40-9)
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BLI 489 Hydrate

Catalog No. B595825 Name Toronto Research Chemicals
CAS Number 623564-40-9 Website http://www.trc-canada.com
M. F. C13H10N3NaO4S Telephone +1 (416) 665-9696
M. W. 327.29097 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 162450

SYNONYMS

IUPAC name
sodium (5R)-6-{5H,6H,8H-imidazo[2,1-c][1,4]oxazin-3-ylmethylidene}-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
IUPAC Traditional name
sodium (5R)-6-{5H,6H,8H-imidazo[2,1-c][1,4]oxazin-3-ylmethylidene}-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
Synonyms
(5R,6Z)-6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt Hydrate

DATABASE IDS

CAS Number 623564-40-9

PROPERTIES

Certificate of Analysis Download
Apperance Yellow Solid
Melting Point >200°C (dec.)
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
BLI-489 is a penem β-lactamase inhibitor, which has shown activity against class A, C, and D β-lactamases. BLI-489 is being tested in combination therapy for drug-resistant bacteria.

REFERENCES

  • Maiti, S., et al.: Curr. Med. Chem., 5, 441 (1998)
  • Barnaud, G., et al.: Antimicrob. Agents Chemother., 48, 1040 (1998)
  • Szabo, D., et al.: J. Clin. Microbiol., 43, 5058 (1998)