3',5'-Bis-O-(tert-butyldimethylsilyl)thymidine-d3

• Catalog No.: B585382
• M. F.: C22H42N2O5Si2
• M. W.: 470.75028

SYNONYMS

• IUPAC name: 1-[(2R,4S,5R)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-5-(^2H₃)methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: 1-[(2R,4S,5R)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-5-(^2H₃)methyl-3H-pyrimidine-2,4-dione
• Synonyms: 3',5'-Bis-O-[(1,1-dimethylethyl)dimethylsilyl]thymidine-d3

PROPERTIES

• Apperance: White Solid
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol

DETAILS

Description (English)

An intermediate in the preparation of deuterated cytidine derivatives

REFERENCES

• Chamorro, C., et al.: Bioorg. Med. Chem. Lett., 11, 3085 (2001)
• Bornemann, B., et al.: Bioorg. Med. Chem., 14, 6235 (2001)
• Desbouis, D., et al.: J. Med. Chem., 51, 6689 (2001)