2-[2-[2-[2-[6-(Biotinylaminohexanoyl]aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid 1,3-Bis[1,6-anhydro-2,3-O-isopropylidene-β-D-mannopyranos-4-yloxy)-2-propylamine Amide

• Catalog No.: B394860
• M. F.: C52H74F3N7O17S
• M. W.: 1158.2408696
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: N-(1-{[(6R)-4,4-dimethyl-3,5,10,11-tetraoxatricyclo[6.2.1.0^2,^6]undecan-7-yl]oxy}-3-{[(6S,7R)-4,4-dimethyl-3,5,10,11-tetraoxatricyclo[6.2.1.0^2,^6]undecan-7-yl]oxy}propan-2-yl)-2-[2-(2-{2-[6-(5-{2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl}pentanamido)hexanamido]ethoxy}ethoxy)ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzamide
• IUPAC Traditional name: N-(1-{[(6R)-4,4-dimethyl-3,5,10,11-tetraoxatricyclo[6.2.1.0^2,^6]undecan-7-yl]oxy}-3-{[(6S,7R)-4,4-dimethyl-3,5,10,11-tetraoxatricyclo[6.2.1.0^2,^6]undecan-7-yl]oxy}propan-2-yl)-2-[2-(2-{2-[6-(5-{2-oxo-hexahydrothieno[3,4-d]imidazolidin-4-yl}pentanamido)hexanamido]ethoxy}ethoxy)ethoxy]-4-[3-(trifluoromethyl)diazirin-3-yl]benzamide

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 57-59°C
• Solubility: Chloroform
• Solubility: DMSO
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A protected, cross-linking, biotin-labelled compound used as an exofacial probe for the human erythrocyte glucose transport system. The compound is impermeable and photolabeling can be confined to the discrete plasma membrane pool of glucose transporters.

REFERENCES

• Holman, G.D., et al.: J. Biol. Chem., 265, 30, 18172 (1990)
• Holman, G.D., et al.: Biochem. J., 269, 615 (1990)
• Koumanov F., et al: Biochem. J. 330, 1209 (1990)
• Hatanaka, Y. et al: Bioorg. Med. Chem., 2, 1367 (1994)