Bicuculline Methiodide

• Catalog No.: B382505
• CAS Number: 55950-07-7
• M. F.: C21H20INO6
• M. W.: 509.29107
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (5S)-6,6-dimethyl-5-[(10R)-12-oxo-3,5,11-trioxatricyclo[7.3.0.0^2,^6]dodeca-1(9),2(6),7-trien-10-yl]-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium iodide
• IUPAC Traditional name: (5S)-6,6-dimethyl-5-[(10R)-12-oxo-3,5,11-trioxatricyclo[7.3.0.0^2,^6]dodeca-1(9),2(6),7-trien-10-yl]-2H,5H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium iodide
• Synonyms: (5R)-5-[(6S)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium Iodide; (-)-Bicuculline Methiodide

DATABASE IDS

• CAS Number: 55950-07-7

PROPERTIES

• Solubility: Methanol
• Solubility: Water
• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 175-177°C
• Solubility: DMSO
• Storage Condition: Refrigerator

DETAILS

Description (English)

GABA receptor antagonist.

REFERENCES

• Curtis, et al.: Nature, 226, 1222 (1970)
• Avoli, M., et al.: J. Physiol. Pharmacol., 75, 526 (1970)
• Chebib, M., et al.: Clin. Exp. Pharmacol. Physiol., 26, 927 (1970)