Bicuculline

• Catalog No.: B382500
• CAS Number: 485-49-4
• M. F.: C20H17NO6
• M. W.: 367.35208
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (10R)-10-[(5S)-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3,5,11-trioxatricyclo[7.3.0.0^2,^6]dodeca-1(9),2(6),7-trien-12-one
• IUPAC Traditional name: bicuculline
• Synonyms: (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one; d-Bicuculline; NSC 32192; (+)-Bicuculline

DATABASE IDS

• CAS Number: 485-49-4

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 193-197°C
• Solubility: Benzene
• Solubility: Chloroform
• Solubility: Ethyl Acetate
• Storage Condition: Refrigerator

DETAILS

Description (English)

Alkaloid naturally occurring in the d-form. Shows GABA antagonist activity.

REFERENCES

• Curtis, et al.: Nature, 226, 1222 (1970)
• Avoli, M., et al.: J. Physiol. Pharmacol., 75, 526 (1970)
• Chebib, M., et al.: Clin. Exp. Pharmacol. Physiol., 26, 927 (1970)