Bexarotene-13C4 Methyl Ester

• Catalog No.: B336757
• M. F.: C30H36O8
• M. W.: 524.60204
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoyloxy}oxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoyloxy}oxane-2-carboxylic acid
• Synonyms: Methyl 4-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-ethenyl]benzoate-13C4; 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-benzoic Acid Methyl Ester-13C4

PROPERTIES

• Apperance: White Solid
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Protected Bexarotene (B336750). Used as an antineoplastic. Also used in the preparation of bexarotene analogs as RXR selective agonists.

REFERENCES

• Wagner, C. et al.; J. Med. Chem. 52, 5950 (2009)
• Boehm, M.F., et al.: J. Med. Che., 37,2930 (2009)
• Gottardis, M.M., et al.: Cancer Res., 56, 5566 (2009)
• Mukherjee, R., et al.: Nature, 386, 407 (2009)
• Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (199