1,6:3,4-Bis-[O-(2,3-dimethoxybutane-2,3-diyl)]-2-O-trifluoromethanesulphonyl-5-O-benzolyl-myo-inositol

• Catalog No.: B427000
• CAS Number: 1068089-34-8
• M. F.: C26H35F3O13S
• M. W.: 644.6085096
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S,3R,5R,6R,8R,9s,10S,12S,13S)-5,6,12,13-tetramethoxy-5,6,12,13-tetramethyl-9-(trifluoromethanesulfonyloxy)-4,7,11,14-tetraoxatricyclo[8.4.0.0^3,^8]tetradecan-2-yl benzoate
• IUPAC Traditional name: (1S,3R,5R,6R,8R,9s,10S,12S,13S)-5,6,12,13-tetramethoxy-5,6,12,13-tetramethyl-9-(trifluoromethanesulfonyloxy)-4,7,11,14-tetraoxatricyclo[8.4.0.0^3,^8]tetradecan-2-yl benzoate
• Synonyms: 1,6-O-[(1R,2R)-1,2-Dimethoxy-1,2-dimethyl-1,2-ethanediyl]-3,4-O-[(1S,2S)-1,2-dimethoxy-1,2-dimethyl-1,2-ethanediyl]-myo-inositol 5-Benzoate 2-(1,1,1-Trifluoro-methanesulfonate)

DATABASE IDS

• CAS Number: 1068089-34-8

PROPERTIES

• Apperance: White Solid
• Melting Point: >150°C (dec.)
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

One of the scyllo-Inositol derivatives having effects on amyloid β peptide aggregation. Scyllo-Inositol has shown promise as a potential therapeutic for Alzheimer's disease, by directly interacting with the amyloid β (Aβ) peptide to inhibit Aβ42 fiber for

REFERENCES

• McLaurin, J., et al.: J. Biol. Chem., 275, 18495 (2000)
• Hardy, J., et al.: Science, 297, 353 (2000)
• Cohen, T., et al.: Biochemistry, 45, 4727 (2000)