3'-p-O-Benzyl-N-desbenzoyl-N-tert-butoxycarbonyl-N,O-isopropylidene-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl} Paclitaxel

• Catalog No.: B288700
• M. F.: C58H66Cl3NO18
• M. W.: 1171.49954
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 5-(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-15-yl 3-tert-butyl (5R)-4-[4-(benzyloxy)phenyl]-2,2-dimethyl-1,3-oxazolidine-3,5-dicarboxylate
• IUPAC Traditional name: 5-(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-15-yl 3-tert-butyl (5R)-4-[4-(benzyloxy)phenyl]-2,2-dimethyl-1,3-oxazolidine-3,5-dicarboxylate

PROPERTIES

• Apperance: White Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A protected Paclitaxel (Taxol) derivative. It can be useful for the treatment of cancer.

REFERENCES

• Xiao, X.-Y., et al.: J. Org. Chem., 62, 6029 (1997).