3'-p-O-Benzyl Paclitaxel

• Catalog No.: B288690
• M. F.: C54H57NO15
• M. W.: 960.02808
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-[4-(benzyloxy)phenyl]-2-hydroxy-3-(phenylformamido)propanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-[4-(benzyloxy)phenyl]-2-hydroxy-3-(phenylformamido)propanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate

PROPERTIES

• Apperance: White Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Protected 3’-p-Hydroxy Paclitaxel (H948895), a metabolite of Paclitaxel.

REFERENCES

• Sonnichsen, D., et al.: J. Pharmacol. Exp. Ther., 275, 566 (1995)
• Walle, T., et al.: Drug Metab. Dispos., 23, 506 (1995)
• Torres, K., et al.: Cancer Res., 58, 3620 (1995)
• Svojanovsky, S., et al.: J. Pharm. Biomed. Anal., 20, 549 (1999).