Bepotastine Besylate

• Catalog No.: B317000
• CAS Number: 190786-44-8
• M. F.: C27H31ClN2O6S
• M. W.: 547.06284
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-{4-[(S)-(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-yl}butanoic acid; benzenesulfonic acid
• IUPAC Traditional name: benzenesulfonic acid bepotastine besilate
• Synonyms: (S)-4-[4-(4-Chlorophenyl-2-pyridylmethoxy)piperidinyl]butyric Acid Benzenesulfonate; Bepreve; 4-[(S)-(4-Chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic Acid Benzenesulfonate; BB; Bepotastine Besilate; Bepotastine Benzenesulfonate; Bepotastine Benzenesulfonate Salt; TAU 284; Talion

DATABASE IDS

• CAS Number: 190786-44-8

PROPERTIES

• Apperance: Off-White to Light Beige Solid
• Melting Point: 144-149·C
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Bepotastine is a histamine H1 receptor anatagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).

REFERENCES

• Kaminuma, O. et al.: Biol. Pharm. Bull., 21, 411 (1998)
• Kitaba, S. et al.: J. Allergy, No pp. given (1998)
• Lyseng-Williamson, K.A., Drugs, 70, 1579 (1998)