[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl[(4-nitro-phenyl)sulfonyl)]amino]propyl]-carbamic Acid tert-Butyl Ester

• Catalog No.: B279070
• CAS Number: 191226-98-9
• M. F.: C25H35N3O7S
• M. W.: 521.6263
• Storage: Refrigerator

SYNONYMS

• IUPAC name: tert-butyl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-nitrobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate
• IUPAC Traditional name: tert-butyl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-nitrobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate
• Synonyms: N-[(1S,2R)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]-carbamic Acid 1,1-Dimethylethyl Ester

DATABASE IDS

• CAS Number: 191226-98-9

PROPERTIES

• Apperance: White Solid
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Storage Condition: Refrigerator

DETAILS

Description (English)

A intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor.

REFERENCES

• Dorsey, B., et al.: J. Med. Chem., 37, 3443 (1994)
• Gong, Y., et al.: Antimicrob. Agents Chemother., 44, 2319 (1994)
• Maeda, K., et al.: J. Biol. Chem., 276, 35194 (1994)