Beclomethasone-d5

• Catalog No.: B131002
• M. F.: C22H29ClO5
• M. W.: 408.91566
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-14,17-dihydroxy-14-[2-hydroxy(^2H₂)acetyl]-2,13,15-trimethyl(6,8,8-^2H₃)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• IUPAC Traditional name: (1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-14,17-dihydroxy-14-[2-hydroxy(^2H₂)acetyl]-2,13,15-trimethyl(6,8,8-^2H₃)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• Synonyms: Becolvent-d5; Beclometasone-d5; 9α-Chloro-16β-methylprednisolone-d5; (11β,16β)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-d5

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 236-238°C
• Solubility: Dioxane
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).

REFERENCES

• Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982)
• Rao, M., et al.: J. Asthma, 19, 21 (1982)
• Small, P., et al.: Ann. Allergy, 49, 127 (1982)
• Brogden, R.N., et al.: Drugs, 28, 99 (1982)