BDP 37

• Catalog No.: B129500
• CAS Number: 191744-13-5
• M. F.: C13H13NO4
• M. W.: 247.24662
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 4,7,11-trioxa-16-azatetracyclo[8.7.0.0^3,^8.0^1^2,^1^6]heptadeca-1,3(8),9-trien-17-one
• IUPAC Traditional name: 4,7,11-trioxa-16-azatetracyclo[8.7.0.0^3,^8.0^1^2,^1^6]heptadeca-1,3(8),9-trien-17-one
• Synonyms: LiD 37; 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one; CX 614

DATABASE IDS

• CAS Number: 191744-13-5

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 149-151°C
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors.

REFERENCES

• Arai, A., et al.: J. Pharmacol. Exp. Ther., 278, 627 (1996)
• Marini, A., et al.: J. Biol. Chem., 273, 29394 (1996)
• Balkowiec, A., et al.: J. Neurosci., 22, 10399 (1996)
• Dicou, E., et al.: Brain Res., 970, 221 (1996)