(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester

• Catalog No.: B121700
• CAS Number: 629652-40-0
• M. F.: C22H19ClN2O5
• M. W.: 426.84966

SYNONYMS

• IUPAC name: methyl (1S,3R)-1-(2H-1,3-benzodioxol-5-yl)-3-(2-chloroacetyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carboxylate
• IUPAC Traditional name: methyl (1S,3R)-1-(2H-1,3-benzodioxol-5-yl)-3-(2-chloroacetyl)-1H,3H,4H,9H-pyrido[3,4-b]indole-2-carboxylate
• Synonyms: (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester; (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester

DATABASE IDS

• CAS Number: 629652-40-0

DETAILS

Description (English)

An intermediate in the preparation of cis-Tadalafil (T004520). A PDE5 inhibitor.

REFERENCES

• Beghyn, T. et al.: Bioorg. Med. Chem. Lett., 17, 789 (2007)
• Daugan, A. et al.: J. Med. Chem., 46, 4533 (2007)