Bay 60-7550

• Catalog No.: B119000
• CAS Number: 439083-90-6
• M. F.: C27H32N4O4
• M. W.: 476.56738

SYNONYMS

• IUPAC name: 2-[(3,4-dimethoxyphenyl)methyl]-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methyl-1H,4H-imidazo[4,3-f][1,2,4]triazin-4-one
• IUPAC Traditional name: 2-[(3,4-dimethoxyphenyl)methyl]-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methyl-1H-imidazo[4,3-f][1,2,4]triazin-4-one
• Synonyms: 2-[(3,4-Dimethoxyphenyl)methyl]-7-[(1R)-1-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one

DATABASE IDS

• CAS Number: 439083-90-6

DETAILS

Description (English)

The compound induced anxiety by inhibition of Phosphodiesterase-2 (PDE2), which regulates cGMP and cAMP signaling.

REFERENCES

• Deguchi, A., et al.: Mol. Cancer Ther., 1, 803 (2002)
• Masood, A., et al.: Eur. J. Pharmacol., 458, 135 (2002)
• Hovatta, I., et al.: Nature, 438, 662 (2002)
• Nikolaev, V., et al.: J. Biol. Chem., 280, 1716 (2002)
• Bouayed, J., et al.: Eur. J. Pharmacol.,