5-Aza-2'-deoxy Cytidine

• Catalog No.: A796950
• CAS Number: 2353-33-5
• M. F.: C8H12N4O4
• M. W.: 228.20528
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-amino-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
• IUPAC Traditional name: 4-amino-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
• Synonyms: DAC; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one; 2-Desoxy-5-azacytidine; β-Decitabine; 2'-Deoxy-5-azacytidine; Dacogen; Decitabine; NSC 127716

DATABASE IDS

• CAS Number: 2353-33-5

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >200°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.

REFERENCES

• Deng, T., et al.: Life Sci., 84, 311 (2009)
• Horne, H., et al.: Mol. Cancer Res., 7, 199 (2009)
• Zinner, R., et al.: Mol. Cancer Ther., 8, 521 (2009)