5-Azacytidine-15N4

• Catalog No.: A796002
• M. F.: C8H12N4O5
• M. W.: 248.17831559
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro(1,3,5-^1^5N₃)-1,3,5-triazin-2-one
• IUPAC Traditional name: 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl](1,3,5-^1^5N₃)-1,3,5-triazin-2-one
• Synonyms: Azacytidine-15N4; NSC 103-627-15N4; Mylosar-15N4; Antibiotic U 18496-15N4; Vidaza-15N4; Azacitidine-15N4; 5-AC-15N4; 5-AZC-15N4; 5-AZCR-15N4; 5-AzaC-15N4; Ladakamycin-15N4; Ledakamycin-15N4; NSC 102816-15N4; U 18496-15N4; WR 183027-15N4; 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one-15N4

PROPERTIES

• Apperance: White Solid
• Melting Point: 222-224°C (dec.)
• Solubility: DMSO
• Solubility: Hot Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.

REFERENCES

• Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999)
• Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999)
• Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999)
• Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)