5-Azacytidine

• Catalog No.: A796000
• CAS Number: 320-67-2
• M. F.: C8H12N4O5
• M. W.: 244.20468
• Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
• IUPAC Traditional name: 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
• Synonyms: 5-AZC; NSC 102816; Azacitidine; Vidaza; Mylosar; 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one; 5-AC; 5-AZCR; 5-AzaC; Antibiotic U 18496; Azacytidine; Ladakamycin; Ledakamycin; NSC 103-627; U 18496; WR 183027

DATABASE IDS

• CAS Number: 320-67-2

PROPERTIES

• Apperance: White-to-Off-White Solid
• Melting Point: 235-237°C
• Solubility: Ethanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)

A potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.

REFERENCES

• Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999)
• Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999)
• Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999)
• Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)