11-Azaartemisinin

• Catalog No.: A794900
• CAS Number: 162791-23-3
• M. F.: C15H23NO4
• M. W.: 281.34742

SYNONYMS

• IUPAC name: (1S,4S,5R,8S,9R,12R)-1,5,9-trimethyl-14,15,16-trioxa-11-azatetracyclo[10.3.1.0^4,^1^3.0^8,^1^3]hexadecan-10-one
• IUPAC Traditional name: (1S,4S,5R,8S,9R,12R)-1,5,9-trimethyl-14,15,16-trioxa-11-azatetracyclo[10.3.1.0^4,^1^3.0^8,^1^3]hexadecan-10-one
• Synonyms: (3R,5aS,6R,8aS,9R,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-1,2-dioxepino[4,3-i]isoquinolin-10(3H)-one; (-)-11-Azaartemisinin

DATABASE IDS

• CAS Number: 162791-23-3

DETAILS

Description (English)

A nontoxic analog of Artemisinin for the oral treatment of malaria.

REFERENCES

• Klayman, D., et al.: Science, 228, 1049 (1985)
• Hu, Y., et al.: Bioorg. Chem., 20, 148 (1985)
• Avery, M., et al.: J. Med. Chem., 36, 4264 (1985)
• Meshnick, S., et al.: Antimicrob. Agents Chemother., 37, 1108 (1985)
• Grace, J., et al.: Xenobiotica, 29, 703