Avibactam-d4 Sodium Salt

• Catalog No.: A794852
• M. F.: C7H10N3NaO6S
• M. W.: 287.22557

SYNONYMS

• IUPAC name: sodium (2S,5R)-2-carbamoyl-7-oxo(3,3,4,4-^2H₄)-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
• IUPAC Traditional name: sodium (2S,5R)-2-carbamoyl-7-oxo(3,3,4,4-^2H₄)-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
• Synonyms: Sulfuric Acid Mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] Ester-d4 Sodium Salt; NXL 104-d4

DETAILS

Description (English)

Labelled Avibactam (A794850). Avibactam (NXL104) is a novel β-lactamase inhibitor with a non-lactam structural scaffold. NXL104 irreversibly inhibits lactamase from Mycobacterium tuberculosis.

REFERENCES

• Iland, C., et al.: J. Pathol. Bacteriol., 58, 495 (1946)
• Flores, A., et al.: Microbiology, 151, 521 (1946)
• Livermore, D., et al.: J. Antimicrob. Chemother., 62, 1053 (1946)
• Tremblay, L., et al.: Biochemistry, 49, 9685 (1946)