Auranofin

• Catalog No.: A794750
• CAS Number: 34031-32-8
• M. F.: C20H34AuO9PS
• M. W.: 678.483871

SYNONYMS

• IUPAC name: gold(1+) ion [(2S,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-[(acetyloxy)methyl]oxan-2-yl]sulfanide triethylphosphane
• IUPAC Traditional name: gold(1+) ion [(2S,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-[(acetyloxy)methyl]oxan-2-yl]sulfanide triethylphosphine
• Synonyms: [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold

DATABASE IDS

• CAS Number: 34031-32-8

DETAILS

Description (English)

Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Aurano

REFERENCES

• Kizu, R., et al.: Chem. Pharm. Bull., 41, 1261 (1993)
• Itokazu, M., et al.: Clin. Ther., 17, 60 (1993)
• Kean, W.F., et al.: Br. J. Rheumatol., 36, 560 (1993)