Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity

• Catalog No.: A791825
• M. F.: C33H34FN2NaO7
• M. W.: 612.6204332
• Storage: Amber Vial, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: sodium 4-[5-(4-fluorophenyl)-5-hydroxy-4-phenyl-2-(phenylcarbamoyl)-1-(propan-2-yl)-3,10-dioxa-6-azatricyclo[4.4.0.0^2,^4]decan-9-yl]-3-hydroxybutanoate
• IUPAC Traditional name: sodium 4-[5-(4-fluorophenyl)-5-hydroxy-1-isopropyl-4-phenyl-2-(phenylcarbamoyl)-3,10-dioxa-6-azatricyclo[4.4.0.0^2,^4]decan-9-yl]-3-hydroxybutanoate
• Synonyms: ATV-FXA sodium salt; 7-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-1b-(1-methylethyl)-7a-phenyl-1a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic Acid Sodium Salt; ATV-cycloIP Sodium Salt

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: >150°C (dec.)
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Amber Vial, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A photodegadation product of Atorvastatin (a cyclic impurity of Atorvastatin).

REFERENCES

• Roger, D., et al.: Clin. Exp. Dermatol., 19, 88 (1994)
• Cosa, G., et al.: Photochem. Photobiol., 80, 159 (1994)
• Kerwin, B., et al.: J. Pharm. Sci., 96, 1468 (1994)