Atorvastatin Calcium Salt

• Catalog No.: A791750
• CAS Number: 134523-03-8
• M. F.: C66H68CaF2N4O10
• M. W.: 1155.3417264
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: calcium bis((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate)
• IUPAC Traditional name: calcium bis(atorvastatin(1-))
• Synonyms: Lipitor; CI 981; Tahor; Sortis; (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; Atorvastatin Hemicalcium; YM 548

DATABASE IDS

• CAS Number: 134523-03-8

PROPERTIES

• Apperance: White Solid
• Melting Point: 176-178°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

REFERENCES

• Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993)
• Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1993)
• Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (1993)