(3S,5S)-Atorvastatin Sodium Salt

• Catalog No.: A791735
• CAS Number: 501121-34-2
• M. F.: C33H34FN2NaO5
• M. W.: 580.6216332
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: sodium (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: sodium (3S,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoate
• Synonyms: (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium; 3S,5S-Atorvastatin Sodium

DATABASE IDS

• CAS Number: 501121-34-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 182-184°C
• Solubility: Chloroform
• Solubility: DMSO
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

REFERENCES

• Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993)
• Heinonen, T.M., et al.: Clin. Ther., 18. 853 (1993)
• Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)