Atazanavir-d5

• Catalog No.: A790052
• M. F.: C38H52N6O7
• M. W.: 704.85548
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: methyl N-[(1R)-1-{[(2S,3S)-3-hydroxy-4-[(2R)-2-[(methoxycarbonyl)amino]-3,3-dimethyl-N'-{[4-(pyridin-2-yl)phenyl]methyl}butanehydrazido]-1-(^2H₅)phenylbutan-2-yl]carbamoyl}-2,2-dimethylpropyl]carbamate
• IUPAC Traditional name: methyl N-[(1R)-1-{[(2S,3S)-3-hydroxy-4-[(2R)-2-[(methoxycarbonyl)amino]-3,3-dimethyl-N'-{[4-(pyridin-2-yl)phenyl]methyl}butanehydrazido]-1-(^2H₅)phenylbutan-2-yl]carbamoyl}-2,2-dimethylpropyl]carbamate
• Synonyms: BMS-232632-d5; CGP-73547-d5; 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-dimethyl Ester, (3S,8S,9S,12S)-2,5,6,13-Pentaazatetradecanedioic Acid-d5

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 197-200°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Newer research has been investigating the potential anticancer effects of atazanavir

REFERENCES

• Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13)
• 853 (13)
• Nolan, D., et al.: Drugs, 63(13)
• 2555 (13)
• Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (13)
• Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (13)