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Apigenin

Catalog No. A726500 Name Toronto Research Chemicals
CAS Number 520-36-5 Website http://www.trc-canada.com
M. F. C23H26N6O2 Telephone +1 (416) 665-9696
M. W. 418.49154 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 160754

SYNONYMS

IUPAC name
4-{6-[(E)-2-[(3-methylphenyl)methylidene]hydrazin-1-yl]-2-[2-(pyridin-2-yl)ethoxy]pyrimidin-4-yl}morpholine
IUPAC Traditional name
4-{6-[(E)-2-[(3-methylphenyl)methylidene]hydrazin-1-yl]-2-[2-(pyridin-2-yl)ethoxy]pyrimidin-4-yl}morpholine
Synonyms
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Pelargidenon 1449
4',5,7-Trihydroxyflavone

DATABASE IDS

CAS Number 520-36-5

PROPERTIES

Certificate of Analysis Download
Apperance Yellow Solid
Melting Point >300°C
Solubility DMSO
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological diffe

REFERENCES

  • Chaumontet, C., et al.: Carcinogenesis, 15, 2325 (1994)
  • Sato, F., et al.: Biochem. Biophys. Res. Commun., 204, 578 (1994)
  • Kuo, M.L. et al.: Biochem. Biophys. Res. Commun., 212, 767 (1995)