Apadenoson-d5

• Catalog No.: A710502
• M. F.: C22H22ClN5O2S
• M. W.: 455.96038
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 3-[7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^2,^6]trideca-2(6),4,7,10,12-pentaen-4-yl]-1-[(^2H₈)morpholin-4-yl]propan-1-one
• IUPAC Traditional name: 3-[7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^2,^6]trideca-2(6),4,7,10,12-pentaen-4-yl]-1-[(^2H₈)morpholin-4-yl]propan-1-one
• Synonyms: DWH 146e-d5; trans-4-[3-[6-Amino-9-[N-(ethyl-d5)-β-D-ribofuranuronamidosyl)]-9H-purin-2-yl]-2-propyn-1-yl]-cyclohexanecarboxylic Acid Methyl Ester; ATL 146e-d5; BMS 068645-d5

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 183-188°C
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

An A2A adenosine receptor agonist. Adjunct to nuclear myocardial perfusion imaging in patients unable to exercise adequately.

REFERENCES

• Bolli, R., et al.: Cardiovasc. Res., 27, 728 (1993)
• Bolli, R., et al.: J. Clin. Invest., 96, 1066 (1993)
• Jordan, J., et al.: J. Pharmacol. Exp. Ther., 280, 301 (1993)
• Rieger, J., et al.: J. Med. Chem., 44, 531 (1993)
• Singh, M., et al.: J. Cardiovasc.