Home > Compound List > Product Information
Anhydro Vinblastine Disulfate Salt_Molecular_structure_CAS_81165-17-5)
Click picture or here to close

Anhydro Vinblastine Disulfate Salt

Catalog No. A659750 Name Toronto Research Chemicals
CAS Number 81165-17-5 Website http://www.trc-canada.com
M. F. C46H56N4O8 Telephone +1 (416) 665-9696
M. W. 792.95884 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 160700

SYNONYMS

IUPAC name
methyl (1R,10S,11R,12R,19S)-11-(acetyloxy)-12-ethyl-4-[(13S,15R)-17-ethyl-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9,16-pentaen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
IUPAC Traditional name
methyl (1R,10S,11R,12R,19S)-11-(acetyloxy)-12-ethyl-4-[(13S,15R)-17-ethyl-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9,16-pentaen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
Synonyms
(+)-Anhydrovinblastine Disulfate Salt
3',4'-Didehydro-4'-deoxyvincaleukoblastine Disulfate Salt
3',4'-Dehydroisoleurosine Disulfate Salt
3',4'-Didehydroisoleurosine Disulfate Salt
3',4'-Anhydrovinblastine Disulfate Salt
3',4'-Dehydrovinblastine Disulfate Salt
Anhydrovincaleukoblastine Disulfate Salt
F 81097 Disulfate Salt

DATABASE IDS

CAS Number 81165-17-5

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point >220°C (dec.)
Solubility Methanol
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
Anhydrovinblastine showed significant cytotoxic potential against a panel of human cancer cell lines and significant activity against the human H460 non-small cell lung carcinoma tumor xenograph in mice.

REFERENCES

  • Koiso, Y., et al.: J. Antibiot., 51, 418 (1998)
  • Olver, I., et al.: Eur. J. Cancer, 43, 1829 (1998)
  • Shao, Y., et al.: Bioorg. Med. Chem., 15, 5061 (2007).