2,5-Anhydro-2,5-imino-D-mannitol

• Catalog No.: A648350
• CAS Number: 59920-31-9
• M. F.: C6H13NO4
• M. W.: 163.17172

SYNONYMS

• IUPAC name: (2R,3S,5R)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
• IUPAC Traditional name: (2R,3S,5R)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
• Synonyms: (2R,3R,4R,5R)-3,4-Dihydroxy-2,5-pyrrolidinedimethanol; 2R,5R-Bis(hydroxymethyl)-3R,4R-dihydroxypyrrolidine

DATABASE IDS

• CAS Number: 59920-31-9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 114-117°C

DETAILS

Description (English)

Many pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and

REFERENCES

• Fellows, L.E., et al.: J. Chem. Brit., 287, (1987)
• Elbein, A.D.: Annu. Rev. Biochem., 56, 497 (1987)
• Fleet, G.W., et al.: J. Chem. Brit., 287, (1989) Baxter, E.W., et al.: J. Org. Chem., 59, 3175 (1987)
• Tyms, A.S. et al. Lancet 1025, (1987)
• Spearman,