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Andrographolide

Catalog No. A637475 Name Toronto Research Chemicals
CAS Number 5508-58-7 Website http://www.trc-canada.com
M. F. C20H30O5 Telephone +1 (416) 665-9696
M. W. 350.4492 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 160619

SYNONYMS

IUPAC name
(4E,5R)-4-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}-5-hydroxyoxolan-3-one
IUPAC Traditional name
(4E,5R)-4-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-hexahydro-1H-naphthalen-1-yl]ethylidene}-5-hydroxyoxolan-3-one
Synonyms
(3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone
Andrographis
[1R-[1α[E(S*)],4aβ,5α,6α,8aα]]-3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone
Andrographolid
3α,14,15,18-Tetrahydroxy-5β,9βH,10α-labda-8(20),12-dien-16-oic Acid γ-Lactone

DATABASE IDS

CAS Number 5508-58-7

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 232-235°C
Solubility DMSO
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M.

REFERENCES

  • Chander, R. et al.: Int. J. Pharmacog., 33, 135 (1995)
  • Chen, H.-W. et al.: J. Nat. Prod., 74, 2408 (1995)
  • J. Agric. Food Chem., 59, 5263 (1995)