Anacetrapib

• Catalog No.: A637200
• CAS Number: 875446-37-0
• M. F.: C30H25F10NO3
• M. W.: 637.508432

SYNONYMS

• IUPAC name: (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-({2-[4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]-5-(trifluoromethyl)phenyl}methyl)-4-methyl-1,3-oxazolidin-2-one
• IUPAC Traditional name: anacetrapib
• Synonyms: (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl]-4-methyl-1,3-oxazolidin-2-one; MK 0859; (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-2-oxazolidinone

DATABASE IDS

• CAS Number: 875446-37-0

DETAILS

Description (English)

An orally active and potent cholesterol ester transfer protein (CETP) inhibitor for the treatment of atherosclerosis, in particular dyslipidemia.

REFERENCES

• Krishna, R. et al.: Br. J. Clin. Pharmacol., 67, 520 (2009)
• Vergeer, M. et al.: Nat. Clin. Pract. Cardiovasc. Med., 5, 302 (2009)
• Masson, D.: Curr. Opin. Invest. Drugs, 10, 980 (2009)