Amrubicin-13C3

• Catalog No.: A635202
• M. F.: C25H25NO9
• M. W.: 486.44526451
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (7S,9S)-9-[(1-^1^3C)acetyl]-9-amino-7-{[(2S,4R,5R)-4,5-dihydroxyoxan-2-yl]oxy}-6,11-dihydroxy-5,7,8,9,10,12-hexahydro(4a,12a-^1^3C₂)tetracene-5,12-dione
• IUPAC Traditional name: (7S,9S)-9-[(1-^1^3C)acetyl]-9-amino-7-{[(2S,4R,5R)-4,5-dihydroxyoxan-2-yl]oxy}-6,11-dihydroxy-8,10-dihydro(4a,12a-^1^3C₂)-7H-tetracene-5,12-dione
• Synonyms: (7S,9S)-9-Acetyl-9-amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione-13C3

PROPERTIES

• Apperance: Orange Solid
• Melting Point: >240°C (dec.)
• Solubility: Chloroform
• Solubility: DMSO
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Synthetic anthracycline antibiotic; inhibits DNA topoisomerase II. Antineoplastic.

REFERENCES

• Igarashi, J., et al.: Bioorg. Med. Chem Lett., 5, 2923 (1995)
• Hanada, M., et al.: Jpn. J. Cancer Res., 89, 1229 (1995)
• Ohe, Y., et al.: Ann. Oncol., 16, 430 (1995)
• Matsunaga, Y., et al.: Ther. Drug Monit., 28, 76 (1995)