Amphotericin B Methyl Ester 90%

• Catalog No.: A634255
• CAS Number: 36148-89-7
• M. F.: C48H75NO17
• M. W.: 938.1056
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate
• IUPAC Traditional name: amphotericin B methyl ester
• Synonyms: Amphotericin B Monomethyl Ester

DATABASE IDS

• CAS Number: 36148-89-7

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: >175°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Amphotericin B Methyl Ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B Methyl Esterin is a cholesterol binding compound that showed inhibiton of human immunodeficiency virus type 1 (HIV-1).

REFERENCES

• Waheed, A.A. et al.: J. Biol. Chem., 281, 28699 (2006)
• Waheed, A. et al.: J. Virol., 82, 9776 (2006)