(S)-Amlodipine Di-p-Toluoyl-D-tartrate

• Catalog No.: A633506
• CAS Number: 1215226-53-1
• M. F.: C40H43ClN2O13
• M. W.: 795.22802

SYNONYMS

• IUPAC name: (2S,3S)-2,3-bis(4-methylbenzoyloxy)butanedioic acid 3-ethyl 5-methyl (4S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC Traditional name: (2S,3S)-2,3-bis(4-methylbenzoyloxy)butanedioic acid amlodipine besylate
• Synonyms: (S)-(+)-Amlodipine Di-p-Tolyoyl-D-tartrate; (4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Di-p-Tolyoyl-D-tartrate; (-)-Amlodipine Di-p-Tolyoyl-D-tartrate

DATABASE IDS

• CAS Number: 1215226-53-1

PROPERTIES

• Apperance: White Solid
• Solubility: Methanol

DETAILS

Description (English)

(S)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

REFERENCES

• Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986)
• Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1986)
• Haria, M., et al.: Drugs, 50, 560 (1986)