(S)-Amlodipine-d4

• Catalog No.: A633493
• CAS Number: 1346616-97-4
• M. F.: C20H25ClN2O5
• M. W.: 408.8759
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 3-ethyl 5-methyl (4S)-2-{[2-amino(^2H₄)ethoxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC Traditional name: 3-ethyl 5-methyl (4S)-2-{[2-amino(^2H₄)ethoxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Synonyms: (R)-(-)-Amlodipine-d4; Levoamlodipine-d4; Lodien-d4; Levamlodipine-d4; (4S)-2-[[2-Amino(ethoxy-d4)]methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester; (-)-Amlodipine-d4; l-Amlodipine-d4

DATABASE IDS

• CAS Number: 1346616-97-4

PROPERTIES

• Apperance: A633493
• Melting Point: 105-107°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A labelled (S)-enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

REFERENCES

• Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986)
• Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1986)
• Haria, M., et al.: Drugs, 50, 560 (1986)