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(S)-Amlodipine-d4_Molecular_structure_CAS_1346616-97-4)
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(S)-Amlodipine-d4

Catalog No. A633493 Name Toronto Research Chemicals
CAS Number 1346616-97-4 Website http://www.trc-canada.com
M. F. C20H25ClN2O5 Telephone +1 (416) 665-9696
M. W. 408.8759 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 160553

SYNONYMS

IUPAC name
3-ethyl 5-methyl (4S)-2-{[2-amino(2H4)ethoxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
IUPAC Traditional name
3-ethyl 5-methyl (4S)-2-{[2-amino(2H4)ethoxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms
(R)-(-)-Amlodipine-d4
Levoamlodipine-d4
Lodien-d4
Levamlodipine-d4
(4S)-2-[[2-Amino(ethoxy-d4)]methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
(-)-Amlodipine-d4
l-Amlodipine-d4

DATABASE IDS

CAS Number 1346616-97-4

PROPERTIES

Certificate of Analysis Download
Apperance A633493
Melting Point 105-107°C
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A labelled (S)-enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

REFERENCES

  • Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986)
  • Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1986)
  • Haria, M., et al.: Drugs, 50, 560 (1986)