2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile Trifluoroacetate _Molecular_structure_CAS_928201-45-0)

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2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile Trifluoroacetate
Catalog No.	A627960	Name	Toronto Research Chemicals
CAS Number	928201-45-0	Website	http://www.trc-canada.com
M. F.	C20H21F4N5O4	Telephone	+1 (416) 665-9696
M. W.	471.4054528	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
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SYNONYMS

IUPAC name

2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)-4-fluorobenzonitrile; trifluoroacetic acid

IUPAC Traditional name

2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl}methyl)-4-fluorobenzonitrile; trifluoroacetic acid

DATABASE IDS

CAS Number

928201-45-0

PROPERTIES

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DETAILS

Description (English)

2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile trifluoroacetate is a potent, selective, and noncovalent inhibitor of dipeptidyl peptidase IV (DPP-4). This inhibitor provides sustained reduc

REFERENCES

Augeri, D., et al.: J. Med. Chem., 48, 5025 (2005)
Drucker, D., et al.: Lancet, 368, 1696 (2005)
Cvetkovic, R., et al.: Drugs, 67, 935 (2005)