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N-(2-Aminophenyl)-N'-phenylheptanediamide_Molecular_structure_CAS_537034-15-4)
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N-(2-Aminophenyl)-N'-phenylheptanediamide

Catalog No. A625980 Name Toronto Research Chemicals
CAS Number 537034-15-4 Website http://www.trc-canada.com
M. F. C19H23N3O2 Telephone +1 (416) 665-9696
M. W. 325.40482 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 160418

SYNONYMS

IUPAC name
N-(2-aminophenyl)-N'-phenylheptanediamide
IUPAC Traditional name
N-(2-aminophenyl)-N'-phenylheptanediamide
Synonyms
N1-(2-Aminophenyl)-N7-phenylheptanediamide

DATABASE IDS

CAS Number 537034-15-4

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 159-161°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Histone deacetylase inhibitor IV. A cell-permeable pimeloylanilide compound that acts as a FXN-(frataxin gene) specific HDAC inhibitor. Reverses the silencing of FXN transcription in FRDA (Friedrich’s ataxia) cells due to hypoacetylation of histones H3 an

REFERENCES

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  • Ferrante, R., et al.: J. Neurosci., 23, 9418 (2002)
  • Gardian, G., et al.: J. Biol. Chem., 280, 556 (2002)
  • Herman, D., et al.: Nat. Chem. Biol., 2, 551 (2002)
  • Beckers, T., et al.: Int. J. Cancer, 121, 1138 (2