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4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine-1-(β-D-ribofuranosyl-5'-triphosphate)_Molecular_structure_CAS_476371-81-0)
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4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine-1-(β-D-ribofuranosyl-5'-triphosphate)

Catalog No. A618360 Name Toronto Research Chemicals
CAS Number 476371-81-0 Website http://www.trc-canada.com
M. F. C21H24N5O13P3 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
({[({[(2R,3S,4R,5R)-5-[4-amino-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
IUPAC Traditional name
({[(2R,3S,4R,5R)-5-[4-amino-3-(naphthalen-1-ylmethyl)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid
Synonyms
3-(1-NM)-PPTP
1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

DATABASE IDS

CAS Number 476371-81-0

PROPERTIES

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DETAILS

Description (English)
An inhibitor scaffolds as new allele specific kinase substrates.

REFERENCES

  • Hunter, T., et al.: Cell, 80, 225 (1995)
  • Liu, Y., et al.: Bioorg. Med. Chem., 6, 1219 (1995)
  • Davies, S., et al.: Biochem. J., 351, 95 (1995)
  • Shah, K., et al.: Chem. Biol., 9, 35 (1995)