9-Amino-1,2,3,4-tetrahydroacridin-1-ol-d3 Hydrochloride

• Catalog No.: A629902
• M. F.: C17H18N2O5
• M. W.: 330.33522

SYNONYMS

• IUPAC name: (2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahydro(1,2,2-^2H₃)acridin-1-ol
• IUPAC Traditional name: 9-amino-3,4-dihydro(1,2,2-^2H₃)acridin-1-ol; maleic acid
• Synonyms: P 83-6029A-d3; Mentane-d3; HP 029-d3; Velnacrine-d3 Maleate; 1-hydroxy tacrine maleate-d3; 9-Amino-1,2,3,4-tetrahydro-1-acridinol-d3 (2Z)-2-Butenedioate; Velnacrine-d3 Hydrogen Maleate

DETAILS

Description (English)

A potential Alzheimer's Disease therapeutic of low toxicity. Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic and without measurable liver toxicity in humans.

REFERENCES

• Alon, R., et al.: J. Cell Biol., 128, 1243 (1995)
• Min, W., et al.: J .Immunol., 159, 3508 (1995)
• Lum, A., et al.: J. Biol. Chem., 277, 20660 (1995)
• Carvalho, F., et al.: J. Appl. Toxicol., 24, 419 (1995)